The pursuit of ageless beauty is an art refined through modern science. At Wise Aesthetics in Carmel, IN, the palette is extensive: from the transformative powers of biostimulators to the subtle enhancements of dermal fillers and the finesse of neuromodulators. Discover how injectables can be the answer to your aesthetic aspirations, painting a masterpiece of youthful radiance.


What Are Biostimulators?

Biostimulators are innovative aesthetic injectables designed to enhance the skin’s natural collagen production. Unlike traditional fillers that add volume directly, biostimulators work beneath the skin to revitalize collagen production, offering gradual and longer-lasting results. They not only restore lost volume but also improve the skin’s texture and elasticity.


Sculptra® stands out in the world of aesthetic treatments as an FDA-approved biostimulator. Made primarily of poly-L-lactic acid, Sculptra® triggers the skin to produce more collagen, gradually restoring facial volume and smoothing out wrinkles and folds. Its benefits unfold over time, ensuring a natural, yet noticeable transformation.

Facial Rejuvenation

Utilizing Sculptra® for facial rejuvenation is akin to turning back the hands of time. By stimulating collagen growth, Sculptra® diminishes facial wrinkles, fine lines, and sagging areas, resulting in a more youthful and refreshed appearance. The treatment is subtle, ensuring changes appear gradually over several months, letting your radiant skin take the spotlight.


In the realm of aesthetic enhancements, BBL, or the Sculptra® Brazilian Butt Lift, is a game-changer. Unlike traditional surgical butt lifts, the Sculptra® BBL employs biostimulators to naturally augment and lift the buttocks. By promoting collagen production in the treated area, Sculptra® offers the dual benefits of adding volume while also improving skin texture. The result is a more sculpted, fuller rear end without the invasiveness of traditional surgery.

Hyperdilute RADIESSE®

Hyperdilute RADIESSE® offers a cutting-edge approach to aesthetic treatments, capitalizing on the power of biostimulatory agents. By integrating calcium hydroxylapatite microspheres into a gel carrier, RADIESSE® provides immediate volumization and stimulates natural collagen production, ensuring results that are both immediate and enduring.

Skin Tightening

Harnessing the capabilities of Hyperdilute RADIESSE®, skin tightening becomes a non-surgical reality. By stimulating collagen synthesis beneath the skin, RADIESSE® helps to tighten sagging skin, rendering a firmer and more youthful appearance. The treatment addresses laxity issues, giving skin a taut, rejuvenated look.

Necklace Lines

Necklace lines, or the horizontal creases on the neck, can betray one’s age. Hyperdilute RADIESSE® targets these signs of aging with precision. When administered, it not only fills these lines but also stimulates the skin’s own collagen, gradually reducing the appearance of these lines and ensuring a smoother, more youthful neck contour.

Hand Rejuvenation

Our hands often show the telltale signs of aging, with skin thinning and veins becoming more prominent. Hyperdilute RADIESSE® offers a solution. By augmenting volume and promoting collagen production, this treatment revitalizes the hands, making them look more youthful and reducing the prominence of veins and tendons. The results are hands that look as youthful and vibrant as you feel.

Dermal Fillers

Dermal fillers have become the cornerstone of non-surgical facial rejuvenation, offering immediate results with minimal downtime. Composed of various substances, these fillers are designed to restore volume, smooth wrinkles, and enhance facial contours, providing a refreshed, youthful appearance. Their versatility and immediate impact make them a sought-after choice for those looking to combat the signs of aging.


JUVÉDERM® stands out in the realm of dermal fillers with its hyaluronic acid-based formulation. Celebrated for its ability to hydrate and volumize the skin, JUVÉDERM® seamlessly fills in wrinkles and fine lines, providing natural-looking results that can last up to a year or more. It offers a suite of injectables, each tailored for specific areas and concerns.


Designed specifically for the mid-face, JUVÉDERM VOLUMA® XC addresses age-related volume loss in the cheeks. This filler not only restores volume but also provides a subtle lift, defining and contouring the cheek area for a youthful profile.


Targeting moderate to severe facial wrinkles and folds, JUVÉDERM VOLLURE® XC offers a softer consistency, making it ideal for areas like nasolabial folds. Its advanced formulation ensures results that are smooth and long-lasting, with a duration of up to 18 months.


JUVÉDERM ULTRA PLUS XC is renowned for addressing deeper facial wrinkles and folds. With a more robust formulation, it offers impressive volume enhancement, making it a favorite for areas that require significant volumization, like the nasolabial folds.


Lips and the surrounding area find a friend in JUVÉDERM VOLBELLA® XC. Specifically formulated for lip augmentation and the smoothing of vertical lip lines, VOLBELLA® XC ensures lips that are fuller, softer, and more defined, with results that can last up to a year.


JUVÉDERM VOLUX™ XC redefines the jawline and chin. Tailored for those seeking a more chiseled profile, this filler adds volume and contours, sculpting the lower face to perfection. The result is a sharper, more youthful visage.


For those desiring plump, luscious lips, JUVÉDERM ULTRA XC is the go-to choice. Designed specifically for lip augmentation, this filler ensures lips that are not only fuller but also maintain their natural movement and feel, making them look effortlessly captivating.


RHA®, or Resilient Hyaluronic Acid, represents the latest innovation in the world of dermal fillers. Crafted to mimic the natural hyaluronic acid found in the skin, RHA® ensures dynamic and adaptable results, adjusting seamlessly to facial movements. This unique attribute ensures not just volume restoration, but also natural expressiveness, striking a perfect balance between rejuvenation and authenticity.

RHA Redensity™

RHA Redensity™ offers a unique combination of hyaluronic acid and a rejuvenating complex of amino acids, antioxidants, minerals, and vitamins. This blend not only provides filler capabilities but also revitalizes the skin, offering a radiant glow. It’s a dual-action solution, addressing volume while enhancing skin quality.


Designed for moderate wrinkles, RHA®2 boasts a fine gel texture, ensuring subtle yet effective results. Perfect for dynamic areas of the face, like the nasolabial folds or marionette lines, RHA®2 adapts fluidly to facial expressions, maintaining a natural appearance even when you smile or frown.


RHA®3 takes on deeper wrinkles and folds with its specialized formulation. Tailored for more pronounced facial lines, its resilient nature ensures that the treated areas remain smooth and volumized, while still allowing for a full range of facial expressions. It’s a blend of restoration with authenticity.


For areas requiring substantial volume and contouring, RHA®4 steps into the spotlight. Designed especially for volumizing and sculpting regions like the cheeks, jawline, or other facial hollows, RHA®4 offers a robust solution that melds seamlessly with the skin, ensuring results that are pronounced yet incredibly natural.


Restylane® is a hallmark in the realm of hyaluronic acid dermal fillers, cherished for its natural-looking results and versatility. By harnessing the power of hyaluronic acid, Restylane® rejuvenates the face by restoring lost volume, smoothing wrinkles, and enhancing facial contours, ensuring a youthful glow without the need for more invasive procedures.


Combining the benefits of Restylane® with the pain-reducing properties of lidocaine, Restylane-L® ensures a comfortable treatment experience. It effectively addresses moderate to severe facial wrinkles and folds, offering results that are both immediate and long-lasting.

Restylane® Lyft

Aimed at restoring volume in the cheeks and hands, Restylane® Lyft provides a dual benefit. On the face, it lifts and contours the cheeks, while on the hands, it minimizes the appearance of wrinkles and veins. It’s the touch of youth for both face and hands.

Restylane® Silk

Crafted specifically for the lips and the lines around them, Restylane® Silk offers finer particles for smooth and natural-looking results. It subtly volumizes the lips and smoothens wrinkles around the mouth, ensuring a soft and silky finish that’s undeniably youthful.

Restylane® Kysse

Celebrate your lips with Restylane® Kysse. Designed for lip augmentation, Kysse adds volume while retaining the lips’ natural movement and texture. The result is plumper, more kissable lips that feel as good as they look.

Restylane® Refyne

Created to address nasolabial folds and marionette lines, Restylane® Refyne uses a unique cross-linking technology that ensures flexibility and natural motion. It smoothens lines while retaining facial expressiveness, striking a perfect balance between correction and movement.

Restylane® Defyne

For deeper laugh lines, Restylane® Defyne offers a robust solution. Its specialized formulation ensures that even pronounced wrinkles are effectively smoothed out, while still allowing for a full range of facial expressions. It’s rejuvenation without compromise.

Restylane® Contour

Chiseling the cheeks and chin becomes a non-surgical reality with Restylane® Contour. This filler excels at enhancing and sculpting facial contours, providing volume where it’s most desired. The outcome is a sharper, more defined profile that radiates confidence.


Sculptra® stands out as a biostimulatory filler, promoting collagen growth. It not only adds volume but also rejuvenates the skin’s underlying structure over time.


RADIESSE offers dual benefits: immediate volume restoration and collagen stimulation. Its calcium hydroxylapatite particles bolster facial areas needing lift and structure.

Hyperdilute RADIESSE®

A variation of RADIESSE, the Hyperdilute form is tailored for skin tightening and addressing more superficial concerns, offering a softer, subtler enhancement.


BELOTERO blends seamlessly with the skin, addressing fine lines and wrinkles. Its smooth consistency ensures a natural-looking finish, making it ideal for delicate facial areas.


Neuromodulators have revolutionized the aesthetic world, providing a non-invasive means to address signs of aging and redefine facial features. By temporarily relaxing targeted muscles, they smoothen wrinkles and modify facial expressions, offering a refreshed appearance.



BOTOX® is the frontrunner in neuromodulator treatments, revered for its capability to soften fine lines and wrinkles. With precise application, it can significantly reduce the appearance of facial lines, providing a smoother, more youthful visage.



Dysport® offers a unique formulation that targets wrinkles by diminishing muscle activity. Particularly effective on forehead lines and crow’s feet, its fast-acting nature ensures results that are both immediate and lasting, maintaining a natural look of vitality.



XEOMIN® sets itself apart by being a highly purified neuromodulator, free from any proteins. This ensures reduced chances of resistance or allergic reactions. Effective in smoothening lines and wrinkles, it offers a clear, refreshed look with each treatment.



DAXXIFY®, a newer entrant in the neuromodulator arena, is gaining traction for its efficacy and consistency. Tailored to address a range of aesthetic concerns, its versatility and results have earned it a growing clientele seeking non-invasive rejuvenation.


Potential Treatments

Neuromodulators aren’t just about erasing lines; their potential treatments span a wide range.


The Basics

At their core, neuromodulators tackle concerns like frown lines, crow’s feet, and forehead lines. They also address bunny lines on the nose, lip lines, and the DAO, which leads to a downturned smile. Chin dimples, a drooping brow, and thin lips can also be refined, making neuromodulators a versatile choice for overall facial rejuvenation.


Slimming the Jawline

By targeting the masseter muscle, neuromodulators can slim the jawline, providing a more oval or heart-shaped face. This treatment is particularly popular among those seeking a softer, more feminine profile.


Nefertiti Lift

The Nefertiti Lift, named after the ancient Egyptian queen, uses neuromodulators to redefine the jawline and neck, counteracting sagging and providing a youthful, lifted appearance. It’s a non-surgical approach to achieving a regal profile.


The Lip Flip

For those desiring a fuller upper lip without fillers, the Lip Flip is the answer. By relaxing the orbicularis oris muscle with neuromodulators, the lip gently rolls out, revealing a subtly plumper pout.



Beyond aesthetic concerns, neuromodulators can also address hyperhidrosis or excessive sweating. By blocking the nerves that activate sweat glands, these treatments provide relief from excessive underarm sweating, ensuring confidence in every situation.


Which Injectables Are Right For You?

Injectables have revolutionized the aesthetic landscape, offering a plethora of options for those seeking rejuvenation without the scalpel. From the collagen-boosting magic of biostimulators to the precise volume enhancements of dermal fillers and the subtle refinements of neuromodulators, the world of injectables caters to diverse aesthetic desires. 

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